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What You Need to Know About the Gastric Sleeve

Posted on November 20, 2019 by

The gastric sleeve, or sleeve gastrectomy, is the new kid on the block so to speak. It’s not a new operation. We used to do the surgeries for other reasons not including weight loss. About 15 years ago a hormone was discovered called ghrelin. It’s a hormone made by part of the stomach that makes you feel hungry. We thought if we took that part of the stomach out, we’ve actually done two things. First we’ve made you a smaller stomach so you can’t eat very much. Secondly, when you take that part of the stomach out, ghrelin levels go way down. Since ghrelin makes you feel hungry, hunger levels go way down in its absence. If you think about it, one of the potential downfalls of every single weight loss plan in the world is hunger. If we can control hunger it’s a lot easier to lose weight and keep the weight off. Sleeve gastrectomy is the fastest growing option out there. It is the most common operation for weight loss right now. Last year about 2/3 of all operations done for weight loss were sleeve gastrectomy in the US. It’s close to 95% of what I do these days because it works so well and we see a quick recovery with very low risk. It keeps your anatomy normal.

In the sleeve gastrectomy, we remove the greater curve of the stomach (stretchy part). If you eat a large meal the stomach fills and stretches way out as you eat. That’s how it can hold so much. When we remove the stretchy part it leaves you with a tubular part (or sleeve). Sometimes when people hear the term sleeve gastrectomy they mistakenly think we’re placing something around the stomach. We’re not placing anything around the stomach. It’s referred to as a sleeve gastrectomy because we’re changing the shape. Like the sleeve on a shirt, it’s tubular shaped. We’re making it into a tubular shape. Nothing is bypassed so there is no malabsorption.  Your anatomy remains normal. Food is going to enter the stomach and empty into the small intestine the same way it did before. The size of the stomach is about the size and shape of a medium banana. The part of the stomach that’s removed is the part that makes the hormone ghrelin. Ghrelin is decreased so hunger decreases. This doesn’t mean that you won’t get hungry. There are still good reasons to get hungry. Your hunger is just much easier to control. This surgery is increasingly popular and the fastest growing option out there. It’s literally close to 95% of what I do nowadays.

The surgery doesn’t take that long. It generally lasts about 45 minutes. 95% of the surgeries we do are outpatient. It’s pretty rare that someone needs to spend the night. Full recovery isn’t as fast as the adjustable bands but it’s a lot faster than gastric bypass. Most people are comfortable driving about 3-4 days after surgery. Generally in 2 weeks people can do most things. In a month you can do anything you want. Recovery tends to be really quick.

What are the risks?  The first 30 days is the same as the other surgeries. It’s just slightly different numbers. In theory the death rate and leak rate should be the same as gastric bypass. But we’re not seeing that. What we’re seeing is about 1:1000 for deaths and less than half a percent for leaks. Wound infections, DVT’s, PE’s and dehydration have fewer risks than gastric bypass because the surgery doesn’t last as long. But it’s not impossible for any of those things. One of the things I really like about this operation is that we’ve gotten rid a lot of the long term risks. You’ve got normal anatomy so once you’re healed, you’re healed. The thing we have to keep in mind is stenosis.   Stenosis means narrowing. Anywhere along the tubular stomach could get scarring and become too narrow. If that happened you would go see a gastroenterologist. They can look in there and take care of it. It would be very rare to need another surgery after the sleeve. In theory stenosis should be about 1%. I’ve done over 1600 of these surgeries. I’ve only seen 1 case of stenosis.

We basically see the same weight loss as we did with the gastric bypass. Average weight loss is 70% of what you were overweight. If you are 100 pounds overweight, your average weight loss will be 70 pounds. If you are 200 pounds overweight, your average weight loss will be 140 pounds. That’s average. Some will lose more and some will lose less. That is very good weight loss. Long-term we see about 10-20% regain most of their weight. With any of these operations you can gain your weight back. Your stomach is a little bigger than with the gastric bypass. So why do we see a similar result?  It’s because ghrelin levels go down. In the other operations, that part of the stomach is still there. We can control the hunger somewhat with appetite suppressants. But they’re not necessarily ideal. With the sleeve gastrectomy ghrelin levels go down and hunger is easier to control.

Overall, for most people considering weight loss surgery, the sleeve gastrectomy is the better option. One of the reasons is we keep the anatomy normal. There’s a lower risk with the procedure, a fairly quick recovery and very good weight loss. We also get rid of any concerns about having anatomic abnormalities or nutritional abnormalities (malabsorption). There’s no mechanical device. Finally, you haven’t burned a bridge. That means if you don’t get out of it what you wanted out of it your anatomy is at least still normal. If your anatomy is still normal you could still have any of the other surgeries done. You could have a band placed on it or converted to a bypass. This is much more difficult after any other the other weight loss surgeries. We haven’t revised these things. We’ve seen really good results with them.

How does CFWLS compare to the national average? Obviously we’re doing this for weight loss to improve medical problems and improve your life.  We’re doing the same thing as everyone else in the world but we’re seeing better weight loss. We have a 15.8% better average weight loss at 2 years. We have good education and weight loss.  We give you a full year afterward. And with that better weight loss we also see better reduction in medical problems:  Diabetes 78.6% vs 62.3%, HTN 62.5% vs 46.9%, lipids 70.7% vs 45.3%, sleep apnea 69.4% vs 56.6%, and GERD 74.3% vs 16.6%.  Some people think weight loss surgery shouldn’t be done on patients with GERD. But we’ve seen it get much better, not worse. Again, it’s not the operation. It’s what you do with the operation. If you do the right things it can fix these medical problems.

Why is the education and support so important? We have Weight Management University for Weight Loss Surgery™.  It’s a 12-month post-op program. It includes all kinds of thing including the following:  pre-op and post-op text books, monthly support group, 12 Weight Management University courses, access to Members Only portal, fitness classes, personal training and more.

View the online surgical webinar and then schedule a call with Cat Williamson to go over any further questions you may have.  You’ll get a copy of my best-selling book, Less Weight…More Life!

Artificial Sweeteners – Pros, Cons and Weight Loss

Posted on June 19, 2019 by

Can they actually help with weight loss? Can they potentially hinder weight loss? So those are some real questions and we will get to them as we go.

Here’s an overview of artificial sweeteners. What role does sugar play in your diet? We will talk about nutritive vs. non-nutritive sweeteners. There is a difference there.  We’ll talk about sugar alcohols and which ones have been around for a while.  Then we’ll discuss saccharin, aspartame, sucralose, and more.  Finally, we will talk about artificial sweeteners and weight gain.

Things have changed over many, many years.  A couple hundred years ago 1800-average consumption of sugar was 25 pounds a year.  By the year 2000, average sugar consumption was 146 pounds a year!  We have an innate desire for sweet things. As we’ve talked about in the past, your body requires NO sugar/carbohydrate to survive. In order to reduce the consumption of sugar other sources of “sweetness” have been developed in hopes that it will be better to have no so much sugar. This came about because we realized that maybe all this sugar isn’t good for us.

We divide sweeteners into nutritive vs. non-nutritive.  Anything that is going to provide us with true nutrition or nourishment is considered a nutritive sweetener.  Foods from food groups (grains, vegetables, fruits, dairy, meat, and oils) provide nourishment and calories so they are considered nutritive.  Products that are added to foods and do not provide any nourishment are considered non-nutritive. FDA places sweeteners under the “GRAS” (generally regarded as safe) list or as “food additives” or “dietary supplements.” It’s thought that they’re safe. We don’t know it absolutely. There may not be a way to study it completely. They can be listed under different things under the FDA. It will depend on what they’re made up of.  Since 1999 at least 10,000 new products containing sweeteners have been launched.  It’s probably close to 15,000 now.

Sugar alcohols are technically a nutritive sweetener because they provide calories (1.5-3 cal/gram). We see a lot of marketing out there. They can be labeled as sugar free. Sugar free doesn’t necessarily mean carbohydrate free.  And, it doesn’t necessarily mean calorie free. Sugar alcohols are neither sugar nor alcohol, but are carbohydrates. Sugar alcohols occur naturally in many fruits and vegetables. That can be the reason why there is some sweetness to some fruits and vegetables. Some of them contain fructose. It’s actually sweeter than other types of sweeteners. Typically sugar alcohols aren’t as sweet as table sugar. Sweetness varies from 25%-100% as table sugar (sucrose).  That means that often a lot more is added to mimic the sweetness. There are lots of examples out there like sugar free gum.  But it’s not carbohydrate free.  The following are sugar alcohols: sorbitol, mannitol, xylitol, erythritol, maltitol, lactitol, and isomalt.  They provide fewer calories than sugar since they are not completely absorbed. Carbohydrate provides 4 calories per gram. Sugar alcohols are typically about 1 ½ -3 calories per gram.  Sugar alcohols have less sugar, but that doesn’t mean they can’t raise your blood sugar. The carbohydrate will eventually be broken down into sugar. They can cause the following side effects: gas, bloating, and diarrhea. Some people are very sensitive to sugar alcohols. Remember: they are NOT calorie free and since not as sweet, you often will eat more.

Saccharin has been around for a long period of time: sweet n’low, Sugar Twin, Necta Sweet.  It’s been around for over 100 years. It was discovered in the 1800’s by researchers working on coal tar derivatives.  It’s calorie free but it does have 200-700 times the sweetness of table sugar. Most of these artificial sweeteners we’re talking about have tremendous amounts more sweetness than table sugar. It tends to have a bitter aftertaste. Originally there was a concern of “bladder tumors in rats” (no increased risk in humans). The researchers gave rats 100X more than any of them could ever actually eat in a day. There’s no way anyone can ever eat this much sugar. When they re-did the study, they found that there were rats that were pre-disposed to getting bladder tumors anyway!  So, the tumors probably had nothing to do with the saccharin. It’s never been shown to cause tumors in humans. If you’re allergic to sulfa medications, potentially you could have an allergic reaction.  It’s very rare, but not impossible.

Aspartame was discovered in 1965 by scientists working on “ulcer drugs.” For some reason they licked their fingers and discovered how sweet it was. It’s now found in over 6000 foods.  Aspartame is Nutrasweet, Equal, and Sugar Twin. They made this by connecting 2 amino acids (aspartic acid and phenylalanine).  These 2 amino acids together have a very sweet taste. Technically it will have calories, but since it’s 200X sweeter than sugar, this amount of calories is miniscule. People with phenylketonuria (PKU) can’t break down phenylalanine. There have been reports of headaches. There are numerous websites that rail against its use. This is the most controversial sweetener. But there’s never been a study that showed that this is a problem. Because it’s just 2 amino acids, there really shouldn’t be a reason for any problems.

Sucralose is Splenda. It was discovered while trying to make a new insecticide. The name is somewhat confusing because it sounds a lot like sucrose. Sucrose is table sugar. They’re two completely different things. Splenda is about 600X the sweetness of sugar.  It can be used for cooking and baking. It’s made from sugar, but it’s nothing like sugar. They chemically altered the sugar and put a chlorine molecule on the sugar, therefore rendering it unable to be absorbed. It’s like a backward or left-handed sugar. You get the taste of sugar, but you don’t get the calories. They added a filler to Splenda called dextrose or maltodextrin to provide bulk and volume.  It’s a marketing ploy that sucralose has not calories but the fillers do have calories. A serving size has not calories which is technically right. However, a serving is less than a teaspoon. A cup actually has about 96 calories and 32 grams of carbs! A cup of sugar has about 768 calories and 192 grams of carbs. So it’s all a marketing ploy with regards to it having no calories.

Acesulfame K (Ace K) was approved in 1988. The K is potassium. It’s 200X sweeter than sugar. It’s often used as a “flavor enhancer.” It’s often put together with another type of sweetener because it tends to make it more palatable. It makes for a synergistic effect. That’s what is used in many of the “zero” sodas. It’s often listed in ingredients as: acesulfame K, acesulfame potassium, ace-k, Sunett, Sweet One, Swiss, Sweet. It does contain a carcinogen called methylene chloride. However, the amounts are so tiny that it’s never really a thought of it causing any problems. It’s been linked to headaches, depression, and nausea. There are minimal studies done to fully evaluate. They’re generally regarded as safe.

Neotame has been FDA approved since 2002 (brand name Newtame). It’s a newer version of Aspartame without the phenylalanine dangers to PKU patients. It’s about 10,000X sweeter than sugar. It’s often used as a “flavor enhancer.” A newer one out there similar to neotame is altitame. It’s amino acids put together: aspartic acid and alanine. It’s 2000X sweeter than sugar.  It’s not been approved in the US yet as far as I know. It very likely will get approved.

Advantame is the cousin to Aspartame. The FDA approved it in May, 2014 (6th one approved). It’s 20,000X sweeter than sugar. It dissolves in water. It doesn’t break down in heat so it can be used in cooking. It does have miniscule amounts of phenylalanine. The “safe” consumption level is >40,000 packets/day. Well good luck with eating 40,000 packets a day! Very unlikely it’s going to cause any problems.

Stevia/Rebiana is one you hear about more and more often. There are many of them out there. They’re all based on the stevia plant. It’s a plant native to South America (Stevia rebaudiana).  They’re starting to grow it more and more places. It’s now being cultivated for harvesting its sweet leaves. The natives used to just pick the leaves and chew on them.  There’s some evidence that potentially it can actually help control blood sugar. It’s 200-300X sweeter than sugar. The working molecule from the plant is called Rebaudioside A. By itself is available as a sweetener labeled as: Only Sweet, Truvia, PureVia, Reb-A, Rebiana, and SweetLeaf. Stevia can be sold as a “dietary supplement.” It’s truly not an artificial sweetener because it comes from a plant. Just because it comes from a plant doesn’t mean it’s necessarily a good thing.  A lot of poisons come from plants too. It doesn’t have any obvious harmful effects. There is a question as to whether it can help with controlling blood sugar. This is probably one of the potentially safer ones out there. There just aren’t a whole lot of studies being done. It’s already approved so who’s going to go back and start doing studies?

A newer one is called Nectresse which is “from the makers of Splenda.” It’s made from Monkfruit, molasses, and erythritol. Monk fruit is about 150X sweeter than sugar. It’s said to have “zero calories” in a packet. Again, that’s somewhat of a marketing ploy. One little packet technically can be called zero calories. That’s not really true because if you’re using it in a large amount (baking) the calories would be there. It’s about 1/3 the calories of table sugar. It’s not technically calorie free because it’s mixed with molasses and monk fruit.

Are artificial sweeteners helpful or a hindrance to weight gain? Research is showing both possibilities. Can we see weight gain or weight loss? It could be both. It may depend on the individual. If you’re taking in fewer calories and using an artificial sweetener it could potentially help you with weight loss. The flip side is it can work against you because artificial sweeteners are so much sweeter than sugar is. They train us to like really sweet things. They may even increase sugar cravings. Sometimes when people are trying to stop sugar cravings they eat other things too that have more sugar and drives the calories up. So it might help with actually keeping the sugar amount lower, but it could cause you to eat more. Also when you get something sweet in your mouth, your body thinks it’s getting sugar. Your body prepares for the sugar coming into the intestinal tract by raising insulin. Potentially artificial sweeteners can raise insulin levels. Insulin is the hormone that tells your body to store fat. Much higher sweetness trains you to prefer sweeter things. It depends what you’re doing with the artificial sweetener. My belief is that if you’re going to use them, use the smallest amount possible. There’s no nutritional value of any artificial sweetener. I would encourage you to experiment. Cut them out and see what happens. If you’ve hit a plateau and can’t figure out what’s going on, artificial sweeteners could be part of your solution.

Any sweeteners are not essential nutrients. They exist to nurture your sweet tooth not your body! Our innate desire for sweetness may be interfering with our ability to judge “good” from “bad.” As a general rule you don’t get something for nothing! I would recommend trying to avoid sugar and artificial sweeteners as much as possible.

If you have questions don’t hesitate to contact us here at The Center for Weight Loss Success.  You can bring your questions when you come in. Stop by and get your free body composition analysis done. You want to preserve lean body mass and get rid of the fat. You should be receiving the weight loss tips and weekly recipes. Subscribe to my weekly webinar each Tuesday at 6pm.Remember it’s your life. Make it a healthy one. Have a good evening everyone. Take care.

Do Growth Hormones Help with Weight Loss?

Posted on May 20, 2019 by

What do you know about growth hormone?  You might hear about this in the media as anti-aging, this wonderful thing that could keep you young forever. It’s not quite like that. But there is some evidence that potentially can be helpful for certain things. We’re going to talk about those things.

If you look at the literature out there, it suggests a lot of wonderful things that growth hormone can do. There are some wide ranges of potential effects. It can: reduce body fat, increase muscle mass, enhance sexual performance, stronger bones, lower cholesterol, lower blood pressure, faster wound healing, higher energy levels, regrowth of vital organs, restore immune function, hair regrowth, sharper vision, elevated mood, and improved cognition. In theory, it sounds like this does all kinds of stuff. So, is this the Fountain of Youth?

Let’s talk about what this is, where it comes from, and what it can potentially do. Is there some way you can actually utilize this? Growth hormone is secreted by the pituitary gland in your brain. The pituitary gland is a tiny little thing separated into an anterior and posterior gland. There are two different lobes. It’s right there at the base of your brain. It’s controlled by the hypothalamus which sends signals down to the pituitary gland and what it should do. The pituitary gland secretes all kinds of different things. Many of them are hormones. We’re talking mainly about the anterior pituitary today. It helps control how your thyroid works, how your adrenal glands work, how the ovaries work (Follicle stimulating hormone), prolactin, and it secretes growth hormone.  It also secretes some other endorphins, which are the feel-good hormones. The anterior pituitary secretes many hormones very important for overall health in addition to growth hormone.

Growth hormone is a peptide that stimulates growth. That means it’s made out of amino acids. It’s a protein. It’s made by the anterior pituitary gland. There are 190 amino acids and it’s a single chain. It’s folded in a particular fashion. A hormone is just a chemical messenger. Once a hormone is secreted (by whatever gland we’re talking about), it passes through the blood stream and sends messages to tissues that have receptors to that hormone.  You have to have receptors on the tissue in order to receive the message. Different tissues may receive a slightly different message to do different things. Basically, this is what all hormones do. Growth hormone is abbreviated HGH. It stands for Human Growth Hormone. You’ll often hear about athletes abusing it to improve their athletic performance. It is a prescription drug and can be used legally for deficiency syndromes. If someone truly has a deficiency syndrome in growth hormone, then potentially they can utilize growth hormone to help fix that deficiency syndrome.

You’ll often hear about it in age management. Part of the reason is, as we get older, just like most hormones, we typically don’t get as much out of our hormones. Hormones are not secreted at the same rate and same amount. The theory is that as we get older and growth hormone decreases, we could possibly prevent some of these aging processes by supplementing growth hormone. This is a very controversial subject. Right now we can’t legally use it unless you have a proven deficiency syndrome. What is a proven deficiency syndrome? If you ask many different experts, you’ll get many different opinions. It is a very controversial medication.

How do you know if you have a deficiency syndrome? It’s not easy to measure. That’s where one of the problems comes in. Growth hormone is released in a pulsatile fashion during the early hours of the deepest sleep. The half-life of growth hormones is very short, so you’d have to catch it at the exact time to know whether you’ve got enough or not. It usually happens in your deep sleep. That’s when it’s released the most. Once it’s secreted by the anterior pituitary gland, it’s taken up by the liver.  The liver converts it into growth factors. Growth hormone by itself is really difficult to measure. You have to catch it at the right time. The half-life is so short. How do you actually measure it? You can measure it in your urine. If you were to collect a 24-hour urine specimen you can look at how much is secreted into the urine. It can give you an idea of whether a person is secreted enough growth hormone. One of the most important growth factors it’s converted into is insulin-like growth factor 1 (IGF-1). We talk about insulin all the time. Insulin is the antithesis of weight loss. We want to keep insulin levels low. This IGF-1 is something different. It just has a name that begins with insulin. It’s insulin-like because insulin is a growing hormone.  With regular insulin it means growing fat. IGF-1 can be a growing factor of growing muscle mass. IGF-1 can be measured because it’s a longer half-life. It will stick around for a longer period of time. If someone were actually had a deficiency syndrome of growth hormone, and we gave them growth hormone, we could get an idea of what the response to that hormone by measuring IGF-1.

Typically growth hormone declines with age. The biggest time to have growth hormone is when we’re growing in adolescence and early adulthood. It declines about 1-3% per year after age 30. It goes down relatively quickly. You’ll see this in Olympians. Typically for men they’re at peak performance in their mid to late 20’s. That’s true with most professional athletes. It happens a little bit sooner with women. The reality is that most of us by the end of our 20’s will start to have a growth hormone decline. We don’t have that same physical performance that we did in our mid to late 20’s. It drops off relatively quickly, but the highest amounts are in the mid to late teens. It can be up to about 3% per year. At some point it will be really low. As we get older we start getting debilitating illnesses. The question is, if we kept supplemented growth hormone higher, could it actually take care of these illnesses of aging?

What are some common signs of low GH? The problem is that most of these signs are really vague because they go along with just feeling bad. The common signs are: premature aging, flabby and obese, stretch marks, droopy eyelids and sagging cheeks, thinning skin, reduced foot arch, thinning muscles of the hands, and prolonged skin folds after pinching skin on the back of the hand. The prolonged skin folds after pinching can also be a sign of dehydration. It could also be a sign of adrenal problems too. Those are really vague things.

What are common complaints with low GH? Again, these complaints tend to be really vague. They don’t mean a whole lot by themselves. The complaints are: poor quality of life, lack of inner peace, anxious, depression, low self-esteem, lack of concentration, lack of self-control, excessive emotions, thinning and weakening of the muscles and skin, exhaustion and poor recovery, feeling of rapidly aging, low libido, and lack of sleep or excessive need for sleep.

What tests can we actually do? GH has a very short ½ life and is released in a pulsatile fashion, so measuring blood levels is impractical and may be meaningless. If someone is measuring your growth hormone and trying to send it off in a lab for bloodwork, it’s pretty much meaningless. IGF-1 can be measured but there is a wide range of “normal.” GH can be measured in 24 hour urine collection, but many labs cannot do this accurately. Almost all of the signs and symptoms of GH deficiency go along with testosterone deficiency. Testosterone deficiency is really common. Both men and women need testosterone. As we age, our testosterone levels drop. Almost every complaint I just mentioned of GH deficiency is actually more likely testosterone deficiency. This might be much more fruitful to measure than to chase GH around.

Let’s say we’re going to treat you for GH deficiency. What are the risks versus the benefits? The benefits are that the complaints we just mentioned could potentially get better. In theory, it’s really safe because we use bio-identical GH. It looks exactly like human GH. If it truly were that unsafe, we would see a lot of younger people with a lot of GH problems because they have really high levels of GH. You don’t want your GH too high either because it could cause Gigantism. Every once in a while you’ll see the 7 foot person that later was diagnosed with a pituitary tumor that secreted GH. Andre the Giant was one of the classic ones. They have a very enlarged jaw and large hands and feet.

Hormone balance is a key concept. We don’t want something out of balance, whether it’s too much or too little. GH has to be given by injection. In theory could we do something to stimulate your own GH? That’s possible in theory. If it’s given by injection, it could take months to notice a clinical improvement. And, this is incredibly expensive. Unless you truly need it and get approval from the insurance company to get treated for this, good luck with getting it paid for! It would be a few thousand dollars every single month. I don’t know many people who are going to do that or want to do that. There’s always the question of because it’s a GH could it actually stimulate tumor growth? If you had some type of tumor, could GH actually make that grow? That’s a real theoretical concern. There’s never going to be a study to look at that. If someone has a tumor we’re not going to start injecting them with GH! It’s been done in animals and was determined it can actually stimulate tumor growth.

Are there certain things that we could do ourselves that would optimize GH release? That would be the optimal thing. What can we do to improve the release of our own GH? We can’t live without it even though our levels go really low with age. Things that improve GH release: strenuous exercise (like High Intensity Interval Resistance Training), deep quality sleep, and protein. These are the best ways. There are a number of potential enhancers. They are: B-vitamins, inositol (like a B-vitamin), minerals (chromium, magnesium, zinc, and iodine. Magnesium also helps with testosterone), amino acids (glutamine 2g/day, carnitine, arginine 7g/day, GABA-all can be found at health food stores), hormones (DHEA, melatonin-helps with sleep-, estradiol, testosterone, thyroid, progesterone), and herbals that can potentially help. Things to avoid: alcohol, caffeine, sugar, and milk products. These are a lot of things we talk about anyway. There are other things that truly inhibit GH release. Carbs-insulin inhibits the release of GH. Stress increases cortisol levels. Cortisol inhibits GH release. If you’re doing things we encourage you to do, you’re probably doing a lot of these things already.

There are some commercial formulas out there. I see this all the time in magazine and newspapers. They say a famous person takes GH and it keeps them young. That’s their secret! What they’re talking about is something that can potentially help increase the release of GH. They tend to be very expensive. They’re usually a mix of amino acids and/or vitamins and herbs. It’s a “proprietary blend.” There are a number of them out there: SeroVital-hgh, Pro-HGH, Symbiotropin, etc.…  They’re combinations that, in theory, that will increase the release of GH. Unfortunately there hasn’t been a lot of evidence that they actually work. There have been a couple of small studies, and they do tend to work in the people that don’t need it! They work really well in young adults, but they’re not GH deficient. Let the buyer beware!  They tend to be very expensive with limited studies that show that they help at all. But they’re not completely lying either because it can help in the people that don’t need it.

In summary, could this GH be the “fountain on youth?” Unfortunately many of these questions are unanswered.  Optimizing your own GH may be helpful in your overall health and weight loss because it does so much that we want to accomplish. For many people the easier answer may be looking at testosterone levels both male and female.  There could be something beneficial there for potential weight loss. It’s something to consider and it’s much easier to measure.

What You Need to Know About Antioxidants

Posted on May 13, 2019 by

Let’s talk about antioxidants. You hear about them in the media. Are these miracle workers or is this just marketing?

The antioxidants kick out the free radicals. These are superheroes!  It’s the epic story of good vs evil. They are the fearless defenders of basically everything.  They can cure cancer, prevent aging, and supercharge your immune system. They basically can do it all, right?! Are these miraculous disease fighting nutrients or over-hyped marketing gimmicks?

What we’re trying to address is the oxidative challenge of life. A paradox of metabolism is that the majority of complex organisms (humans) require oxygen.  Oxygen is a highly reactive molecule that not only sustains life but also produces reactive oxygen species: hydroxyl radical (OH) and super-oxide anion (O2-). They are free radicals. These free radicals are by-products of our energy producing process (cellular respiration). Cellular respiration is how the cells produce energy and sustain life. We can’t live without this happening on a cellular level. The trick is to keep these highly reactive free radicals under control to prevent cellular damage. These free radicals can cause cellular damage. It’s thought that this cellular damage done by the oxygen-free radicals can cause a lot of health problems. We want to keep them under control. Antioxidants can potentially help us here.

Are you getting “rusty?” I wanted to find a simplified version to think about this. Oxygen and iron produce rust. You can actually do it without the oxygen.   In order for rust to form we have to have oxygen available. Are these oxygen free radicals causing some damage within our body? That’s the real question.  Just like the Tin-Man got squeaky in the Wizard of Oz, potentially we may need to be oiled up a little bit. What are the ways we can prevent this damage from occurring?

What are antioxidants? The oxidants are producing damage. Antioxidants may be able to prevent that.  They are molecules that are capable of inhibiting the oxidation of other molecules. If you’re inhibiting the oxidation of other molecules, we’re preventing the rust. Oxidation is a chemical reaction that transfers electrons from one substance to another. They’re just moving electrons around. Part of this is that oxidation reactions are crucial for life (respiration and production of energy). If we’re not doing this, we are dead. We can’t live without it, but we want to prevent the damage. When we’re breathing in and out oxygen is travelling throughout our body. Every single cell in our body needs it because oxidation reactions are crucial for life. We want to limit the by-products that can cause damage. So, the oxidation can produce these free radicals. These oxygen free radicals can lead to chain reactions that cause cell damage and cell death. These oxygen free radicals are even more reactive than oxygen is. They can cause damage. We don’t want to cause damage to the DNA. When the cells re-produce and there’s damage to the DNA, potentially you’ve cause damage that will keep on going. Tumor cells can come from normal cells. There’s DNA damage and all of a sudden they’re growing out of control. Antioxidants can stop some of these chain reactions. It does this by removing the free radical intermediates. It’s done by giving up electrons. Then it can stop these reactions by occurring.

We can think of antioxidants in two different ways. They’re either Hydrophilic or Hydrophobic. Hydro means water.  Phyllic means loves water. Hydrophobic means fear of water. Some work well with water and others do not work well with water. There are different types of antioxidants and they’ll do different things in different parts of your cell. They specifically can do different things for different reactions. They want to neutralize these free radicals.

Where do these free radicals come from? Typically they come from different things in our life.  It could come from the following things: ultraviolet rays, atmospheric pollution, stress, and poor nutrition. All these things affect all of our cells. They can cause free radicals. If these free radicals occur they can cause cellular damage. We want to protect these cells with antioxidants.

How does an antioxidant work? For an oxygen free radical to form, the molecule has to lose an electron. Then it becomes unstable, thus becoming the “free radical.” They want to steal an electron from somewhere. They try to steal it from some nearby molecule. This causes a chain reaction. It can go all through the cell and cause cellular damage. An antioxidant is an electron donor. It can donate an electron and still remain stable. It has to be able to donate an electron to these free radicals and still remain stable. This stops the damage.  The antioxidants bind to the free radicals to form stable molecules. Stable molecules will prevent the damage. It’s a relatively simple concept. It’s not quite that simple in chemistry.

What are common antioxidants? There are a lot of them out there but many vitamins are antioxidants. Vitamin C is one of the best out there. Vitamin A and the carotenoids are antioxidants.  Those are found in the following: carrots, squash, broccoli, sweet potatoes, tomatoes, kale, collards, cantaloupe, peaches, apricots (bright colored fruits and veggies).  You’ll find that many of these antioxidants occur naturally in bright colored fruits and vegetables.  Vitamin C is found in citrus fruits, green peppers, broccoli, leafy veggies, strawberries and tomatoes. I don’t encourage people to eat a lot of fruit, especially if they’re sensitive to carbohydrates. Vitamin E is a fat-soluble vitamin found in nuts and seeds, green leafy veggies, vegetable oil, and liver oil. It’s in a lot of things that we typically eat. We talked about selenium with thyroid. It’s very important for thyroid function. It’s found in the following: fish, shellfish, red meat, grains, eggs, chicken, and garlic. There are a lot of vitamin-like antioxidants. You’ll sometimes see these sold as antioxidants. Coenzyme Q10 is very important. It can be helpful if you’re on a cholesterol medication (statin). If you’re on a statin you ought to be taking Coenzyme Q10 because there’s a lot of damage that occurs in the cells with statins. Coenzyme Q can offset that. It’s an important carrier in mitochondria during energy synthesis. Glutathione is often sold in health food stores because it’s a good antioxidant. The problem is that it’s digested in the intestinal track so you don’t just absorb it. You have to eat the precursors that can make the glutathione. It’s an electron donor and can be increased by supplementing with ALA, melatonin, and milk thistle. Flavonoids/Polyphenols are in a lot of whole foods. They are found in soy, red wine, purple grapes, pomegranate, cranberries, and tea. You’ll often see on the labels, “high in flavonoids.” Lycopene you’ll see on every ketchup bottle in the world. It’s in tomato and tomato products, pink grapefruit, and watermelon. Lutein is found in dark green veggies such as kale, broccoli, kiwi, brussel sprouts, and spinach. Lignan is in flaxseed, oatmeal, barley, and rye.

There are antioxidant enzymes made by the body. These enzymes can help produce the antioxidants. Superoxide Dismutase (SOD) stabilizes that superoxide anion. It can donate electrons. Catalase is another enzyme that converts H202 (hydrogen peroxide) to O2 (oxygen) and H2O.  Glutathione peroxidase also breaks down H2O2 to O2 to H2O. The simplified definition of an antioxidant is they are electron donors. They stabilize potentially damaging molecules. Are there health benefits? Yes!

Where are the best antioxidants? Not necessarily in a pill form. Just like when we talked about fiber. The best fiber comes from food. The best antioxidants come from food. It’s the bright colored veggies and fruits (be careful if you’re carb sensitive) that are very high in antioxidants.

You’ll often see what’s called anti-aging antioxidants. It’s a lot of marketing but there’s something to it.   I think a lot of the damage of aging is these oxygen free radicals. They can cause damage to the cells, specifically the DNA, and then cause aging. Can we prevent that by taking antioxidants? Most things that have antioxidants in them are very healthy. I encourage you to eat these foods but they’re not necessarily going to stop the aging process. These foods are: acai berry, pomegranate, passion fruit, blueberries, kiwi, cranberries, apricots, prunes, and more. If they’re whole foods, they will typically contain antioxidants. Dark chocolate contains antioxidants. Just a little though…

There are a lot of common myths about antioxidants. Part of that is free radicals must be destroyed! Again, as we mentioned at the beginning, free radicals are actually normal byproducts of normal metabolism. If we stop that, we’d be dead. We can’t stop that and we don’t want to stop that. We want to do it in a controlled manner.  Another myth is that all antioxidants are created equal. All these different foods have different antioxidants in them. They have different jobs. You want to get your antioxidants from a broad variety of foods. Another myth is that all antioxidants come from fruits and veggies. That’s not true because you can find them in meat, dairy, and eggs. Typically whole foods are a good source. The next myth is antioxidant fortified foods are healthier. There’s no evidence of this. You can get the antioxidants from whole foods. Adding more antioxidants to those foods has never been shown to be healthier. The last myth was a theoretical concept a few years ago. The myth is if I exercise and take antioxidants I will become super fit. However, the way muscle function improves is to have some stress on the muscle in order for function to improve. That’s why when we exercise we get sore.  A little bit of soreness is good.  A lot of soreness is not so good. The way we improve from a fitness standpoint is that you need to have some muscle growth there. Part of the way a muscle grows is by undergoing stress. To improve muscle function it is some of the result of this oxidative stress. If we prevent the oxidative stress during exercise you could potentially doing yourself more harm than good. You need to stress the muscle. Just be careful. You don’t want to injure yourself. Some of the best fitness gains occur during the aerobic into the anaerobic energy systems. By taking antioxidants, it may be harder for that to happen.

Here are a few tips for success! Eat your colorful veggies! The evidence is mixed about whether taking antioxidant supplements is beneficial. There’s never been a big study that’s shown that it’s really helpful. Eat the whole foods.  Most of what you see is marketing! The “Basics” is always important: eat right, exercise daily, take your vitamins, get plenty of rest, and handle stress. You have to do these things right. Throwing some supplements on top of that is not doing a whole lot to help. Adding antioxidants to the “Basics” potentially will be helpful. I will encourage you to go the whole food route.

If you have any questions don’t hesitate to leave a message below or email them to Success@CFWLS.com. Also if you think of some once we’re all done, give us a yell and we’ll answer them. Stop by the Center for Weight Loss Success and get your Body Composition Analysis done. You need to make sure you’re losing fat and preserving lean body mass.